Senior Research Associate, Flow Cytometry
Job Description
<div class="content-intro"><p></p> <p><strong>Company Overview:</strong></p> <p>Beam Therapeutics is a biotechnology company committed to establishing the leading, fully integrated platform for precision genetic medicines. To achieve this vision, Beam has assembled a platform with integrated gene editing, delivery and internal manufacturing capabilities. Beam’s suite of gene editing technologies is anchored by base editing, a proprietary technology that is designed to enable precise, predictable and efficient single base changes, at targeted genomic sequences, without making double-stranded breaks in the DNA. This has the potential to enable a wide range of therapeutic editing strategies that Beam is using to advance a diversified portfolio of base editing programs. Beam is a values-driven organization committed to its people, cutting-edge science, and a vision of providing life-long cures to patients suffering from serious diseases.</p> <p></p></div><p><strong>Primary Responsibilities:</strong></p> <ul> <li>Supporting all internal/external research programs.</li> <li>Execute specimen preparation, staining and sample acquisition of flow cytometric data.</li> <li>Perform cell sorting on BD FACS Melody, FACSAria Fusion or BD FACS Symphony S6.</li> <li>Design, plan, and execute assay development and/or platform development within the core flow cytometry group and cross-functionally.</li> <li>Perform flow data analyses and interpretation, and present data at group meetings.</li> <li>Maintain electronic notebook record of performed experiments.</li> <li>Provide basic training to researcher on various flow cytometers and cell sorters.</li> <li>Evaluate and troubleshoot instrument issues.</li> <li>Assist in coordinating core lab logistics (e.g. user scheduling, vendor/maintenance calls, etc.)</li> </ul> <p><strong>Qualifications:</strong></p> <ul> <li>Bachelor’s degree (or foreign equivalent) with five years of progressive, post-baccalaureate experience, or a master’s degree (or foreign equivalent) with two years of progressive, post-baccalaureate experience, with degree fields in biology, immunology, cell biology, molecular biology, pharmaceutical sciences, biochemistry, biomedical engineering, biotechnology or a closely related field, and demonstrated experience in all of the following:</li> </ul> <p>(a) performing high-parameter flow cytometry analyses of hematopoietic stem and immune cell subsets, and,</p> <p>(b) designing and executing flow-based assay development for preclinical or translational research; and,</p> <p>(c) conducting quantitative flow cytometry data analysis using FlowJo or FCS Express; and,</p> <p>(d) troubleshooting instrument performance and coordinating maintenance; and,</p> <p>(e) operating and maintaining high-parameter flow cytometers and cell sorters.</p> <p><strong>Other Information:</strong></p> <ul> <li>Permanent, full-time, immediately available, job opportunity;</li> <li>Does not require travel (role is substantially laboratory-based, in-house);</li> <li>Not permitted to telecommute, i.e., cannot exclusively work remotely from home;</li> <li>Must live in the City of Cambridge, MA, or within a reasonable, daily commuting distance thereof (e.g., areas contemplated can include the City of Boston, the larger Greater Boston region, or Massachusetts’ MetroWest, North or South Shore communities);</li> <li>Beam’s headquarters is at 238 Main Street, Cambridge, MA 02142 and this is the primary worksite for the role long-term; and</li> <li>Role is not a supervisory role and does not have subordinate